Pharmacogenomics
Pharmacogenomics is the branch of pharmacology that deals with the influence of genetic variations on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug efficacy or toxicity. It aims to develop rational ways to optimise drug treatment according to the patient's genotype, to ensure maximum efficacy and minimal adverse effects. These approaches promise the advent of personalised medicine, in which drugs and drug combinations are optimised for the unique genetic make-up of each individual. Pharmacogenomics is the application of pharmacogenetics to the whole genome, examining the interactions between a single gene and drugs.
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